EFFICACY AND SAFETY OF DR. ORTHO OIL IN THE TREATMENT OF JOINT PAIN, STIFFNESS, AND INFLAMMATION: AN OPEN-LABEL, NON-RANDOMISED CLINICAL STUDY

Abstract

Background: Joint pain or inflammation is a common complaint among the elderly and is conventionally treated with steroidal or non-steroidal anti-inflammatory drugs (NSAIDs). Because of the adverse effects of these drugs, the present herbal formulation is being developed for the long-term control of pain and inflammation. Objective: The objective of this study was to assess the efficacy and safety of Dr. Ortho Oil in patients with knee pain, low back pain, joint stiffness, sports injuries, and joint inflammations. Methods: This was a single-centre, open-label, non-randomised study. 120 participants were selected based on the inclusion and exclusion criteria. All individuals were instructed to use Dr. Ortho Oil for 60 days. The primary outcome was a change in the frequency of subjects with a significant reduction in joint pain, stiffness, and inflammation. Secondary outcomes were improvements in investigator assessment scale (IAS) and subject self-assessment questionnaire (SAQ) scores at successive administrations compared with the baseline. Results: The study indicated that topical use of Dr. Ortho Oil for 30 days reduced all dimensions of pain. SAQ and IAS scores also decreased significantly.