Abstract
<p>Acne having a prevalence of &gt; 90% in adolescents persisting in adulthood, causes inflammation and scaring. Acne scars cause severe social, psychological and cosmetic problems. There are many remedies available for acne scars with variable results. CO2-AFR laser is a new modality with more effectiveness and low side effect profile.</p><p><strong>Objective:</strong><strong> </strong>To determine the effectiveness and safety of CO2-AFR device in the treatment of moderate to severe atrophic acne scars.</p><p><strong>Study Design:</strong><strong> </strong>Interventional study.</p><p><strong>Place and Duration of Study:</strong><strong> </strong>This study was conducted at Dermatology Department Unit-I, Mayo Hospital Lahore and duration was 1 year, from April 2015 to March 2016.</p><p><strong>Material and Methods:</strong><strong> </strong>The 30 patients of either sex, having moderate to severe atrophic acne scars were enrolled in the study. Pretreatment assessment of acne scars was done by using Goodman &amp; Baron qualitative scarring grading system. Patients were treated at 4 – 5 weeks interval with maximum 5 sessions. Objective assessment for efficacy and side effects was done at each session. Data was collected on a specially designed proforma and statistical analysis carried out by using SPSS version 17.</p><p><strong>Results:</strong><strong> </strong>Significant improvement in acne scars was observed. 14 (46.7%) patients showed good efficacy (50 – 75% reduction), 1 (3.3%) patient came out with excellent efficacy (&gt; 75%) and 14 (46.7%) patients showed fair efficacy (25 – 50% reduction in acne scars). 13.3% patients showed few delayed side effects which resolved with treatment.</p><p><strong>Conclusion:</strong><strong> </strong>CO2-AFR device was proved to be effective and safe in the treatment of moderate to severe atrophic acne scars.</p>
Highlights
Acne has a prevalence of > 90% in adolescents,[1] persisting in adolescence in almost 12%-14% of cases with severe social, psychological and cosmetic implycations.[2]
Material and Methods: The 30 patients of either sex, having moderate to severe atrophic acne scars were enrolled in the study
Free fatty acids are produced, as a result of enzymes released from bacteria, which lead to inflammatory lesions
Summary
Acne has a prevalence of > 90% in adolescents,[1] persisting in adolescence in almost 12%-14% of cases with severe social, psychological and cosmetic implycations.[2]. Lesions with inflammation can lead to scarring.[3]. Free fatty acids are produced, as a result of enzymes released from bacteria, which lead to inflammatory lesions. These inflammatory lesions can heal with scarring. Acne scars can be atrophic (89 – 90%) and hypertrophic.[5] There are several classifications of acne scars, whereby scars are named as rolling, icepick, shallow boxcar and deep boxcar.5Rolling scars are Mshaped, gently undulating like hills and valleys withoutsharp borders. Icepick scars are V-shaped, known as pitted scars, appear as round, deep depressions with a pinpoint base. Boxcar scars are U-shaped, usually round, polygonal or linear at the skin surface. Boxcar scars are the most common type, followed by rolling and icepick scars.[5,6]
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