Efficacy and safety of Bi qi capsules in the treatment of lumbar disc herniation: A meta-analysis

Abstract

Background: At present, traditional Chinese medicine has attracted widespread attention in the treatment of lumbar disc herniation (LDH). Clinical studies have found that the efficacy of Bi qi Capsules on LDH is inconsistent. Therefore, this study systematically evaluated Bi qi Capsules or combined with conventional treatment. Meta-analysis was performed on the efficacy of LDH drugs, visual pain simulation (VAS) score, Japanese Orthopaedic Association Scores JOA score, and adverse reactions. Methods: Eight databases of CNKI, VIP, Wan fang Data, CBM, PubMed, Web of science, Embase, and Cochrane Library were searched for randomized controlled trials of Jin bi qi capsules or combined conventional treatment of LDH from the database establishment to June 2022. The efficacy, VAS score, JOA score and adverse reactions of Bi qi Capsules on LDH were evaluated by random effects model system for meta-analysis. Results: Six studies with 642 participants, 306 in the treatment group and 336 in the control group, were included in this study. Compared with the control group, the effective rate and JOA score of Bi qi Capsule or combined with conventional treatment of LDH were significantly improved, the VAS score was significantly lower than that of the control group, and the occurrence of adverse reactions was not significantly different from that of the control group. Conclusion: Bi qi Capsule is safe and effective in the treatment of LDH and can significantly reduce pain and improve lumbar function.