Efficacy and Potential of Stem Cell Therapy for Alzheimer’s Disease

Abstract

Alzheimer’s Disease (AD) is characterized primarily by the buildup of beta-amyloid plaques and tau proteins. It is a very common neurodegenerative disease that is marked by cognitive decline, neuronal and synaptic loss. AD pathology is not fully understood and there is currently no cure. The disease is terminal and devastates the lives of many. Stem cell therapy involves the use of stem cell’s properties of regeneration and repair to reverse the damage of many diseases. The application of stem cell therapy to AD seems to have the promise to mitigate and reverse the onset of AD. Animal models have displayed the effectiveness of stem cell therapy towards AD by improving cognitive performance and promoting neurogenesis. The abilities and applications of stem cell therapy seem to be highly promising despite having bottlenecks. The difficulties in controlling differentiation due to complexities in controlling the process is the primary issue presented. With the use of stem cell therapy for AD, it is also possible to adapt the technology to various other neurodegenerative diseases and various diseases overall.