Abstract
Objective: To study the clinical effect of TCM syndrome differentiation and treatment on pneumoconiosis. Methods: Randomly selected 160 cases of pneumoconiosis patients admitted to our hospital, stratified randomly divided into the experimental group and the control group;The control group was given conventional oxygen and nursing therapy,the experimental group on the basis of the control group was given TCM syndrome differentiation. Two groups of patients had to finished the SGRQ before and after treatment, And use the method of immunofluorescence to check out the content of procollagen type III(PCIII), collagen type IV(IV-C), hyaluronic acid(HA) and laminin(LN) in serum in the two groups of patients before and after treatment. Two groups of clinical effect will been judged in one month. Results: The two groups in age, the cumulative dust length, the content of four parameters of fibrosis in serum, SGRQ each score and total score had no difference(P>0.05); In the two groups after treatment, there is difference on the content of PCIII in serum, respiratory symptoms, sickness influence and total score, with statistical significance(P<0.05). The experimental treatment efficiency is higher than the control group treatment efficiency. Conclusion: Traditional Chinese Medicine syndrome differentiation and treatment on pneumoconiosis, can delay the development of patients ' condition, have the effect on easing patients' clinical symptoms, and have no obvious adverse reactions.
Highlights
Pneumoconiosis is due to the long-term inhalation of productive dust in professional activities, and retention in the lung, mainly diffuse fibrosis of lung tissue caused by systemic diseases[1]
The deficiency of lung-qi cause further the symptoms of kidney deficiency. It follows that the development of pneumoconiosis is the chronic evolution process that deficiency develops in lung, spleen and kidney, and cause deficiency in five organs; dryness-heat, phlegm and blood stasis and weakened body resistance are three key for the pathogenesis of pneumoconiosis[7,8]
Cases source: randomly selected 160 cases of pneumoconiosis patients admitted to Qingdao city center hospital, during the period of 2015.7 to 2016.7. 112 cases of one phase of the pneumoconiosis, 29 cases of two phase of the pneumoconiosis, 19 cases of three phase of the pneumoconiosis. stratified randomly divided into experimental and control group, 102 cases of the experimental group, 58 cases of the control group, approximation ratio 2:1.Cases selected conditions: On the basis of the pneumoconiosis diagnosis standard(GBZ 70-2009) in the diagnosis of pneumoconiosis patients
Summary
Pneumoconiosis is due to the long-term inhalation of productive dust in professional activities, and retention in the lung, mainly diffuse fibrosis of lung tissue caused by systemic diseases[1]. Pneumoconiosis once occurred, a progressive development, endanger the health of the workers exposed with dust and reduce the labor ability and quality of life, and cause huge economic loss to the country[2,3]. At present, It is lack of effective treatment methods in the treatment of pneumoconiosis, application of western medicine treatment of pneumoconiosis is given priority to with glucocorticoid and immunosuppressants at home and abroad , due to its side effect is remarkable, and its treatment effect is not ideal, its application is limited for certain in clinical. In the year of 2015-2016, Application of TCM syndrome differentiation in 160 cases of patients with clinical curative effect analysis in our hospital, curative effect is satisfied, report as follows
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