Efficacy analysis of preserved great burdock essence compounds

Abstract

In our previous study, we developed the great burdock essence compounds successfully. Clinical trial has proved that great burdock can function as an adjuvant therapy for patients with gastric ulcer caused by Helicobacter pylori. This study aims to assess the storage stability of great burdock essence compounds. We used the high-performance liquid chromatography method to test the concentration of chlorogenic acids at different times in the long-term storage test and accelerated storage test, and observed their appearance. The results showed that the concentration of chlorogenic acids degraded from 29.29 ± 0.49 μg/g to 28.29 ± 0.40 μg/g during the accelerated storage tests conducted for up to 6 months. In addition, the concentration of chlorogenic acids degraded from 29.29 ± 0.49 μg/g to 28.57 ± 0.21 μg/g during the long-term storage tests conducted for a period of up to 12 months. In both these tests, no change was observed in trait, scent, and color of the great burdock essence compounds. These results suggest that these compounds are highly stable.