Abstract

The cellular effects of three alkaloids isolated from Strychnos usambarensis (melinonine F, strychnofoline, 18-19-dihydro-usambarine) are analysed by cytological methods in experimental animal tumours cultivated in vitro (B 16 mouse melanoma cells, mouse Ehrlich tumour cells ELT, HW 165 rat hepatoma). Under some experimental conditions, a certain degree of antimitotic activity is demonstrated.

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