Efferocytosis of oxidized low-density lipoprotein generated apoptotic bodies by primary M1 and M2 macrophages isolated from non-obstructive and obstructive coronary artery disease patients

Abstract

Efficient efferocytosis performed by macrophages is a key determinant to maintaining plaque stability in coronary artery disease (CAD) via the process of clearing the apoptotic bodies accumulated in atherosclerotic plaque.