Abstract
Aim: To evaluate the effects of whey protein (WP) supplementation (1.24mg/g, 24days) in rats with autism spectrum disorder (ASD) induced by valproic acid (400mg/kg, single dose). Materials & methods: Wistar rats (14days old) were divided into four groups: control, ASD, ASD plus WP andWP. Results: WP increased bacterial diversity and the number of colonies. Bacteria from the Firmicutes phylum were predominantly found in the supplemented groups (p<0.05). WP also improved the animals' memory in the Y-maze test and decreased the time thatmale animals spent in the 'solitary chamber'(p<0.05). Conclusion: WP supplementation positively influenced gut microbiota, along withmemory.
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