Abstract
Objectives:This study aimed to examine the effects of wet-to-dry bandages for the treatment of surgical wounds in goats.Materials and Methods:Three types of bandages, i.e., the calcium alginate gel, the homogenous platelet-rich plasma (PRP) gel dressing, and saline dressing, were used to promote the healing process for the management of wounds. Artificial circular wounds were created and treated with bandages to evaluate their effects on the wound healing process in 12 goats. The morphological parameters, i.e., diameters (cm), duration of healing, and wound contraction (cm), were evaluated to differentiate the postoperative sequelae on wound healing process up to day 30 in three different treatment groups of goats. Tissue specimens from the wounds were examined histopathologically on 1st, 3rd, 7th, and 30th postoperative days. Finally, the obtained data were analyzed using the Statistical Package for the Social Sciences 19 software.Results:The current study revealed that the contraction diameter was higher in calcium alginate gel and PRP gel treated group when compared to the saline dressing group. Aggregation of immunoreactive cells (neutrophils, macrophages, and lymphocytes), collagen fiber bundles among the cells, and proliferation of blood vessels were observed in the epidermis of calcium alginate gel, PRP gel treated and saline dressing wounds, which promote the healing process of wounds. In visual inspection, the number of reactive cells and proliferation of blood vessels were higher in the calcium alginate gel and PRP gel treated group than the saline dressing.Conclusion:In terms of epithelialization, epidermal characteristics, neovascularization, and infiltration of immunoreactive cells, the calcium alginate gel and the homogenous PRP gel dressings showed the best healing performance. Therefore, the present study suggests that clinicians could consider the calcium alginate gel dressing and homogenous PRP gel dressing as beneficial for wound care.
Highlights
The wound is a type of injury to the body that occurs from violence, accidents, or surgery that usually entail lacerations or breaking of a skin membrane and damage to underlying tissues, complexed with the involvement of profound structures, i.e., muscles, bones, tendons, nerves, and vessels [1]
The current study revealed that the contraction diameter was higher in calcium alginate gel and platelet-rich plasma (PRP) gel treated group when compared to the saline dressing group
Based on the application of bandages, the experimental animals were divided into three groups, i.e., saline dressing, calcium alginate gel dressing, and PRP gel dressing in skin wound healing process
Summary
The wound is a type of injury to the body that occurs from violence, accidents, or surgery that usually entail lacerations or breaking of a skin membrane and damage to underlying tissues, complexed with the involvement of profound structures, i.e., muscles, bones, tendons, nerves, and vessels [1]. It may be caused by physical, chemical, and thermal means. Effects of wet-to-dry bandages on second intention healing of surgical wounds on the skin of goats. J Adv Vet Anim Res 2020; 7(4):647654
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of advanced veterinary and animal research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
