Abstract
Moringa oleifera is used in folk medicine for the treatment of many ailments among which, hypertension and intestinal disorders. The aim of this study was to investigate the hypotensive and/or antihypertensive activity of Moringa oleifera leaf extract on normotensive anaesthetized rats by direct measure of the arterial pression and in the other hand, to determine its antispasmodic effects on isolated rat duodenum. Intravenous administration of aqueous leaf extract of Moringa oleifera (EAMO 5mg/kg -75 mg/kg body weight), caused a transitory dose-dependent fail in the mean arterial blood pressure of normotensive anaesthetized rats (p< 0.05). Moreover, hypertensive arterial blood pressure induced by phenylephrine 100µg/kg rat body weight, was completely abolished by aqueous extract of Moringa oleifera 10mg-40mg/kg body weight. The studies on isolated rat duodenum smooth muscles demonstrated that the aqueous extract of Moringa oleifera produced a dose dependent relaxation of these muscles (p
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
