Effects of virus hepatitis on postoperative recovery of patients with esophageal cancer

Abstract

Objective To investigate the effects of virus hepatitis on the postoperative recovery of patients with esophageal cancer. Methods The clinical data of 217 patients undergoing radical resection for esophageal cancer between January 2012 and August 2015 were retrospectively analyzed. Patients were divided into non-hepatitis group (n=206) and virus hepatitis group(n=11), and the incidence of postoperative anastomotic fistula, healing of incision, volume of pleural effusion, time of chest tube placement and postoperative hospitalization days were compared between two groups. Results The incidences of postoperative anastomotic fistula and unfavorable healing of incision in virus hepatitis group were significantly higher than those in non-hepatitis group(27.3% vs 5.8%, χ2=17.53, P<0.01; 36.4% vs 5.3%, (χ2=15.26, P<0.01). After exclusion of patients with anastomotic fistula, the time of chest tube placement, volume of pleural effusion and postoperative hospitalization days in virus hepatitis group were significantly longer or higher than those in non-hepatitis group[(7.2±3.5)d vs (4.4±2.7)d, t=1.782, P=0.036; (3 870±1 036)ml vs (1 360±870)ml, t=3.370, P<0.01; (21.5±6.3)d vs (15.6±2.8)d, t=2.012, P=0.029]. Conclusions Virus hepatitis especially complicated with liver dysfunction can significantly increase the incidence of postoperative anastomotic fistula, volume of pleural effusion, incidence of incision, time of chest tube placement and postoperative hospitalization days in patients undergoing radical resection for esophageal cancer. Key words: Virus hepatitis; Esophageal cancer; Postoperative effects