Abstract
Abstract We investigated the effects of acetylsalicylic acid, salicylic acid, sulfisoxazole, and phenobarbital—at concentrations at or just above those in serum after therapy—on results of the 2-(4'-hydroxyazobenzene) benzoic acid (HABA) and bromcresol green (BCG) methods for measuring serum albumin. Although the HABA method was more prone to such interference, only interference by salicylic acid with the HABA method is significant. Salicylic acid at a concentration of 400 mg/liter decreases the apparent values for HABA-albumin by about 10%.
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