Abstract
BackgroundRemineralization of incipient caries is one of the goals in dental health care ,especially in pediatric dentistry. The present study aimed at comparing the effects of MI varnish (3M (United states)) , Nano paste( FGM(Brezil) ), 5% sodium fluoride varnish) DuraphatColgate (united states) ) on remineralization of enamel lesions.Material and MethodsIn this in-vitrostudy, 60 intact human pre-molars, were randomly allocated to four groups of 15. Baseline surface microhardness in three points in the center of the polished area was measured. After two days of immersion in demineralizing solution, microhardness of all samples was measured. Afterward, groups 1-3 under-went treatment with MI varnish, nano paste, 5% sodium fluoride varnish and then again microhardness was measured. The results were analyzed by one-way analysis of variance (ANOVA), repeated measures ANOVA, and Bonfreni table was used.ResultsDuraphat varnish in comparison with control group, significantly increased surface microhardness and in comparison with Nano and MI paste varnish groups significant differences was shown between groups. (P< 0.05). MI paste varnish and Nano paste similary showed more increases in surface microhardness in comparison with Duraphat varnish and control groups (P≈1).ConclusionsAccording to the results of this study, all three varnishes, Duraphat , MI paste and Nano paste increase the enamel surface microhardness and remineralization of incipient caries. MI paste and Nano paste compared to Duraphat Varnish, significantly showed more increases in enamel surface microhardness but Nano paste and MI paste were almost the same. Key words:CPP-ACP, Nano varnish, fluoride varnish, microhardness, demineralization, remineralization.
Highlights
Dental caries is a chronic, multifactorial, transmissible, infectious disease which occurs when the presence of acids on the tooth-plaque interface and leads to a shift in the demineralization/remineralization equilibrium favoring a net demineralization of the enamel [1,2]
The casein phosphopeptide– amorphous calcium phosphate (CPP-ACP) complex acts as a reservoir for storing bioavailable calcium and phosphate and maintains the solution supersaturated, reinforcing remineralization [11]
One-way analysis of variance (ANOVA) results indicated no significant differences in the mean baseline (p=0.323) and after two days of demineralization microhardness (P =0.429 ), but significant differences was observed in microhardness after remineralization process (P< 0.05)
Summary
Dental caries is a chronic, multifactorial, transmissible, infectious disease which occurs when the presence of acids on the tooth-plaque interface and leads to a shift in the demineralization/remineralization equilibrium favoring a net demineralization of the enamel [1,2]. The Nano-HAP paste contains calcium nanophosphate organized in a crystalline form of hydroxyapatite and 9,000 ppm of fluoride (Desensibilize Nano P, FGM, Joinville, Santa Catariuna, Brazil) This agents indicated for desensitization and/or remineralization of the enamel and is commercially available for professional use [15]. Considering the limited research on the effectiveness of this newly introduced product, the present study aimed at comparing the effects of MI varnish (3M(United states)), Nano paste(FGM(Brezil)) and Duraphat (Colgate(united states)) on remineralization of enamel lesions. The present study aimed at comparing the effects of MI varnish (3M (United states)) , Nano paste( FGM(Brezil) ), 5% sodium fluoride varnish) DuraphatColgate (united states) ) on remineralization of enamel lesions. Conclusion: According to the results of this study ,all three varnishes, Duraphat , MI paste and Nano paste increase the enamel surface microhardness and remineralization of incipient caries. MI paste and Nano paste compared to Duraphat Varnish, significantly showed more increases in enamel surface microhardness but Nano paste and MI paste were almost the same
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