Abstract

BackgroundAnxiety, an important factor that affects the therapeutic effect and preservation rate of methadone maintenance treatment, has a high prevalence among MMT patients. This study aims to investigate the effects of treatment status and life quality on anxiety in MMT patients.MethodsOne hundred and Seventy-seven methadone maintenance treatment users in Guangzhou, China were evaluated. The socio-demographic, duration and MMT-related characteristics were documented. Anxiety level and quality of life were evaluated by Beck Anxiety inventory (BAI) and the Quality of Life-Drug Addiction (QOL-DA) respectively. The correlation between different factors and BAI score was also analyzed.ResultsThe BAI total score and the QOL-DA score were 7.1±8.2, 163.5±21.4 respectively. 30.5% of the subjects showed mild to severe anxiety. Treatment interruption and QOL-DA score had strong correlations with the score of BAI, with correlation coefficients of 0.17 and − 0.08 respectively.ConclusionsAnxiety symptoms were commonly presented in MMT patients. Treatment interruption and quality of life are two major factors affecting anxiety of MMT patients.

Highlights

  • Anxiety, an important factor that affects the therapeutic effect and preservation rate of methadone maintenance treatment, has a high prevalence among MMT patients

  • This study focuses on the effects of treatment status and quality of life which gives a good assessment of the patient’s condition on anxiety in MMT patients

  • There were 177 methadone maintenance treatment users enrolled in the study of which 155 were male (87.6%) and 22 were female (7.5%)

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Summary

Introduction

An important factor that affects the therapeutic effect and preservation rate of methadone maintenance treatment, has a high prevalence among MMT patients. This study aims to investigate the effects of treatment status and life quality on anxiety in MMT patients. Methadone maintenance treatment (MMT), a substitutive therapy, has been proved helpful in reducing opioid abuse, drugrelated risk behaviors, the infection rate of AIDS and crimes [3,4,5], as well as improving patiIt is noteworthy that some researches indicated thatent’s overall wellbeing [6]. It was reported that over 18% among MMT patients has anxiety symptom [8,9,10,11, 12]. Anxiety increase the risk of injection practices, HIV infection and criminal behaviors among MMT patients [10].

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