Effects of training on body composition, blood lipids, and glucose homeostasis assessed by the homeostasis model assessment

Abstract

Summary Objective To determine effect of aerobic exercise training on glucose homeostasis, body composition and lipid profile in presence of obesity. Methods A total 34 middle-aged (43 ± 3 years) obese men (BMI = 32.1 ± 2.9 kg/m 2 ) were divided into exercise (3 months aerobic exercise, three times weekly) or control (detraining) group. Fasting glucose, triglyceride (TG), high-density lipoprotein ( HDL ) , beta-cell function and anthropometrical indexes measured before and after aerobic exercise intervention or detraining in exercise and control group respectively. Statistical analysis was performed with the SPSS software version 15.0 using an independent paired t -test. The P -value Results There are no differences in anthropometrical or biochemical variables in baseline in two groups ( P ≥ 0.05). Exercise intervention led to significant decrease in fasting glucose, TG, TG/HDL ratio, systolic blood pressure and all anthropometrical indexes in exercise group ( P P P P ≥ 0.05). Conclusion Despite no significant change on insulin resistance in response to aerobic exercise training in middle-aged obese males, but was associated with an improvement in body composition and lipid profile and particularly fasting glucose in these subjects. It seems that reduction in blood glucose has occurred in response to increased insulin secretion of pancreas beta-cells.