Effects of topical application of growth factors followed by microneedle therapy in women with female pattern hair loss: A pilot study

Abstract

canaliculi). They present at or shortly after birth, and most cases are associated with other systemic conditions. Uncombable hair syndrome is similar to APKH; however, the SEM cross-section appears triangular, which is different from the presentation of APKH. Diffuse partial woolly hair (DPWH) and environmental factors such as trauma, radiation and drugs should also be ruled out. DPWH comprises predominantly normal straight hairs intermingled with thinner curly hairs. DPWH usually involves the whole hair shaft and patients complain of hair loss. Acquired progressive kinking of the hair can progress to hair thinning and androgenetic alopecia or resolve to normal hairs. Better prognosis may be expected in female or prepubertal patients and those with involvement of non-androgen-dependent areas of the scalp. There are no effective treatments for APKH. Topical minoxidil is regarded as an alternative treatment; however, it is generally unable to prevent androgenetic alopecia. Ki-Hun SONG, Jin PARK, Seok-Kweon YUN, Han-Uk KIM, Ji-Hyun YI Department of Dermatology, Research Institute of Clinical Medicine, Chonbuk National University Medical School, and Jun & Jung Dermatologic Clinic, Jeonju, Korea