Abstract
SummaryThe administration of thiouracil to the male rat results in a pronounced atrophy of the adrenal glands and an initial increase in ascorbic acid concentration in the adrenals followed by a return to normal values. Surgical thyroidectomy produces a less pronounced adrenal atrophy but a greater adrenal inhibition as revealed by a final decrease in adrenal ascorbic acid concentration. The effects of both types of induced hypothyroidism on the adrenals may be prevented by the administration of thyroxin. It is concluded that adrenal ascorbic acid concentrations are reliable indices of adrenocortical activity only if interpreted in terms of change in adrenal size.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
