Effects of Three Different Modes of Resistance Training on Appetite Hormones in Males With Obesity.

Ali Ataeinosrat,Mitra Khademosharie,Trisha A Vandusseldorp,Sadegh Amani-Shalamzari,Hossein Abednatanzi,Mohammad Soltani,Ali Mossayebi,Akbar Nouri-Habashi,Hassane Zouhal,Marjan Mosalman Haghighi,Ayoub Saeidi,Abbass Ghanbari-Niaki,Kelly E Johnson

doi:10.3389/fphys.2022.827335

Abstract

PurposeThis study explored the effect of three different modes of resistance training on appetite hormones [leptin, ghrelin, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), and peptide tyrosine–tyrosine (PYY)], cardiometabolic and anthropometric measures in males with obesity.MethodsForty-four males with obesity (age: 27.5 ± 9.4 yrs.; mean weight: 93.2 ± 2.2 kg, body mass index: 32.9 ± 1.2 kg/m2) were randomized to traditional resistance training (TRT, n = 11), circuit resistance training (CRT, n = 11), interval resistance training (IRT, n = 11) or control (C, n = 11) groups. All resistance training groups received 50 min of supervised training per session, three days per week, for 12 weeks. Measurements were taken at baseline and after 12 weeks of training.ResultsPlasma levels of leptin, ghrelin, CCK, and PYY decreased significantly in all three different modalities of resistance training groups when compared to the control group (p < 0.05). GLP-1 increased significantly in both CRT and IRT groups compared to TRT and C groups (p < 0.05). Glucose-dependent insulinotropic polypeptide decreased significantly in CRT and IRT groups compared to the C group (p < 0.05). Adiponectin levels increased significantly in all resistance training groups compared to the C group (p < 0.05).ConclusionOverall, CRT and IRT protocols had the greatest impact on appetite hormones compared to individuals who engaged in TRT or did not exercise (C).

Highlights

Obesity is a global crisis that affects all ages and socioeconomic groups, and it is one of the major health concerns of the 21st century
Glucose-dependent insulinotropic polypeptide decreased significantly in circuit resistance training (CRT) and interval resistance training (IRT) groups compared to the C group (p < 0.05)
Overall, CRT and IRT protocols had the greatest impact on appetite hormones compared to individuals who engaged in traditional resistance training (TRT) or did not exercise (C)

Summary

Introduction

Obesity is a global crisis that affects all ages and socioeconomic groups, and it is one of the major health concerns of the 21st century. According to the World Health Organization estimates, more than 1.9 billion adults aged 18 years and older are overweight, and of those, over 650 million are obese (Haththotuwa et al, 2020). An unhealthy lifestyle, including low levels of physical activity and high quantities of food intake, is one of the main key factors accelerating the expansion of obesity (Kim et al, 2019). The hypothalamus integrates the neuronal and hormonal signals and controls eating behaviors, satiety, and caloric intake (Zouhal et al, 2019). The main hormones regulating appetite and satiety are leptin, ghrelin, glucagon-like peptide-1 (GLP-1), peptide tyrosine–tyrosine (PYY), glucose-dependent insulinotropic polypeptide (GIP), and cholecystokinin (CCK; Zanchi et al, 2017)

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