Abstract
Methods Between January 2016 and October 2018, sixty-four consecutive patients who underwent a total of 66 stenting procedures were screened for symptomatic and asymptomatic atherosclerotic VAOS. Of these patients, 57 had complete follow-up data. The baseline patient demographics and morphological features of the VAO were recorded. Potential factors influencing ISR, including conventional cerebrovascular disease risk factors, were assessed, together with outcome events including recurrent transient ischemic attack (TIA), stroke, and vascular-related mortality. Results The average follow-up period was 13.2 ± 4.6 months. Technical success was achieved in all interventions. The degree of stenosis was reduced from 77.2 ± 6.1% to 13.7 ± 8.9% after the procedure. ISR was detected in eight treated vessels (14.0%) and occlusion in two (5.3%) arteries. Of the 57 patients, one had an ischemic stroke and 5 had TIAs. The angle of the VAO at the subclavian artery was associated with the risk of restenosis (preoperative, P = 0.04; postoperative, P = 0.02). Conclusions Stenting is a feasible and effective treatment for VAOS. The angle of the VAO at the subclavian artery may contribute to the development of ISR.
Highlights
Atherosclerotic stenosis of the vertebral artery ostium (VAO), a recognized cause of ischemic stroke, accounts for 5.2–9% of posterior circulation ischemic strokes [1, 2]
Stent implantation for VAO stenosis (VAOS) is a safe option for reducing the long-term risk of stroke [9, 10]; in-stent restenosis (ISR) is more common for stents placed at the origin of an artery than in those placed in the intracranial vertebral artery (VA) [11]
There was no association between ISR after VAO stent implantation and age, sex, risk factors, rate of stenosis, location of stenting, stent diameter, stent length, or VAO tortuosity (Table 1)
Summary
Atherosclerotic stenosis of the vertebral artery ostium (VAO), a recognized cause of ischemic stroke, accounts for 5.2–9% of posterior circulation ischemic strokes [1, 2]. The effect of the VAO/subclavian artery angle in VAOS stent patients is seldom mentioned. This prospective, single-center study evaluated the incidence of and factors associated with ISR in 57 consecutive patients who underwent VAO stent placement. Between January 2016 and October 2018, sixty-four consecutive patients who underwent a total of 66 stenting procedures were screened for symptomatic and asymptomatic atherosclerotic VAOS Of these patients, 57 had complete follow-up data. Of the 57 patients, one had an ischemic stroke and 5 had TIAs. The angle of the VAO at the subclavian artery was associated with the risk of restenosis (preoperative, P = 0:04; postoperative, P = 0:02). The angle of the VAO at the subclavian artery may contribute to the development of ISR
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
