Abstract

Stroke holds the third position globally as a cause of combined morbidity and mortality, presenting a dire prognosis. This study aims to investigate the hypothesis that nurse-led rehabilitation and follow-up programs offer a significant improvement in motor disability outcomes in post-stroke patients compared to standard care. Eligibility criteria required primary studies providing data on post-stroke patients managed via nurse-led programs or standard care. Comprehensive searches were conducted across several databases until June 2023. The bias and quality of the included studies were assessed using appropriate tools. Our study analyzed a total of 16 studies involving 2072 patients. The findings suggested that nurse-led programs significantly correlate with overall motor disability improvements compared to standard care, as reflected by higher Barthel index (BI) scores, improved modified BI scores, and reduced proportions of patients with a modified Rankin scale of >2. Nurse-led programs are associated with overall improvements in motor disability in post-stroke patient management and follow-up, proving to be more effective than standard care. We recommend that the nurse-led programs be clearly defined, isolated from the multidisciplinary teams, and specified in one study arm to draw significant results regarding their roles in managing post-stroke patients.

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