Abstract

Withania somnifera (Ashwagandha) root extract contains lot of biologically active metabolites, which have a broad range of pharmacological activities. The current study was designed to evaluate the effects of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, thermal and behavioral properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts – one part was control without any Biofield Energy Treatment and another part was treated with the Energy of Consciousness Healing Treatment remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect® treated sample. The PXRD analysis exhibited that both the treated and control samples were amorphous in nature. The particle size values at d10, d50, and d90 of the treated sample were decreased by 8.41%, 0.51%, and 7.88%, respectively compared with the control sample. The surface area analysis revealed that the surface area of the treated sample was significantly increased by 5% compared to the control sample. The FT-IR analysis indicated the alteration of the force constant for the functional groups of the treated sample in comparison to the control sample. The UV-vis analysis revealed that the wavelength for the maximum absorbance of the control and treated samples were at 205.3 and 205.0 nm, respectively. The TGA analysis revealed that the total weight loss was decreased by 0.65% in the treated sample compared with the control sample. The DSC analysis indicated that the onset, peak, and endset vaporization temperature of the treated sample were significantly increased by 41.97%, 23.51%, and 8.82%, respectively as compared to the control sample. The latent heat of vaporization (∆H) of the treated (239.96 J/g) sample was significantly increased by 39.84% compared with the control (171.60 J/g) sample. This indicated that the treated sample was thermally more stable as compared to the control sample. The current findings suggested that The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) might have the astounding capacity to enhance the solubility, absorption, dissolution, and bioavailability of ashwagandha root extract in various form of pharmaceutical and nutraceutical formulation by modifying its particle size and surface area. Thus, the treated ashwagandha root extract might provide better therapeutic response against against inflammatory diseases, immunological disorders, stress, arthritis, cancer, diabetes, sexual disorders, aging and other chronic infections.

Highlights

  • The importance of the herbal medicines in the prevention and treatment of the various diseases have been increased day-by-day throughout the world due to its impressive therapeutic effects and fewer side effects as compared to the modern medicines [1]

  • The test compound was divided into two parts, one part of the test compound was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) by renowned Biofield Energy Healers and defined as The Trivedi Effect® treated sample, while the second part of the test compound did not receive any sort of such treatment and defined as untreated or control ashwagandha root extract sample

  • The current research work revealed that The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) has the outstanding capability for reduction of the particle size of the ashwagandha root extract along with enhanced surface area

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Summary

Introduction

The importance of the herbal medicines in the prevention and treatment of the various diseases have been increased day-by-day throughout the world due to its impressive therapeutic effects and fewer side effects as compared to the modern medicines [1]. Ashwagandha is widely used in the most of the Indian herbal drugs and nutraceuticals for the treatment of various diseases including nervous and sexual disorders, infectious diseases, diabetes, cancer, ulcer, immunological disorders, stress, arthritis, etc. As ashwagandha root extract contains a wide array of nutrients and phytochemicals, it is used as a dietary supplement for the health restoration [3]. The major active phytoconstituents of ashwagandha root extract are highly oxygenated withanolides. The oxidation at various sites of skeleton is responsible for the structural deviations in different classes of withanolides [11,12,13,14]

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