Abstract
(1) Background: The aim of this study was to assess the preventive effect of tooth surface disinfection treatment, in addition to fluoride application, during fixed orthodontic treatment. (2) Methods: An open label randomized control trial for the evaluation of the dental caries preventive procedure was performed for the patients with high caries risk who had been visited at Department of Orthodontics, Tsurumi University Dental Hospital for orthodontics treatment. The follow-up period was six months. White spot lesions (WSLs) were evaluated by quantitative light-induced fluorescence (QLF). Cariogenic bacteria were monitored and evaluated by bacterial culture. In addition, the oral microbiome was evaluated by a next-generation sequence (NGS). (3) Results: By the mixed effect modeling, tooth surface disinfection treatment significantly reduced cariogenic bacteria and all parameters obtained by QLF. (4) Conclusions: Tooth surface disinfection treatment, in addition to PMTC and fluoride application, were effective for dental caries prevention and keeping a healthy microbiome during orthodontic treatment.
Highlights
Publisher’s Note: MDPI stays neutralOne of the goals of orthodontic treatment is to correct malocclusion and deformities to improve dental esthetics [1]
Despite the post-therapeutic esthetic advantages of orthodontics, the treatment is associated with an increase in dental caries incidence since orthodontic brackets tend to retain dental biofilm [2] and interfere with proper tooth cleaning [3,4]
It has been suggested that the risk of white spot lesions (WSLs), dental caries, and periodontal complication are caused by the change in oral microbiome [7]
Summary
One of the goals of orthodontic treatment is to correct malocclusion and deformities to improve dental esthetics [1]. Fixed orthodontic appliances are a common and effective tool to treat malocclusion. They have side effects such as a change of the composition of oral microbiome [5,6]. The complicated undercut shape of fixed orthodontic appliances makes teeth cleaning more difficult and can induce dental plaque accumulation [2,4]. It has been suggested that the risk of white spot lesions (WSLs), dental caries, and periodontal complication are caused by the change in oral microbiome [7]. Previous studies have suggested that an increase in mutans streptococci, with regard to jurisdictional claims in published maps and institutional affiliations
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
