Abstract

Background: Tetrahydroxystilbene glucoside (TSG), the main active ingredient derived from the dried tubor root of Polygonum multiflorum, presents different pharmacological activities such as anti-oxidant and anti-inflammation. Recent studies indicated that TSG produced neuroprotection against Parkinson’s disease (PD). However, few researches focusing on the effects of TSG on the liver cytochrome P450 (Cyp) enzyme expressions in PD animal model were also shown. Keywords: Tetrahydroxystilbene glucoside, rat liver, dopaminergic neuronal damage, cytochrome P450, protein expression, rats.

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