Abstract
Effects of supplementing lactic acid bacteria on fecal microbiota, total cholesterol, triglycerides and bile acids in rats.
Highlights
Cholesterol is the archetypical steroid in mammals
In a previous study, we investigated the cholesterol-lowering effect of lactic acid bacteria screened from Inner Mongolia native meat sausages in China
To verify our in vitro results and investigate the effectiveness of L. p X3-2B ingestion in decreasing the risk of atherosclerosis, we investigated the cholesterol-lowering effect of fecal micro biota, triglycerides (TG), total cholesterol (TC) and total bile acid, in rats to further characterize factors affecting and correlation of its ability to hydrolyze cholesterol
Summary
Cholesterol is the archetypical steroid in mammals. Hyper cholesterol associated with cardiovascular disease is one of the most important causes of death (Yıldız, Öztürk and Aslım 2011, Zhang et al 2012). Bile-salt hydrolase activity is observed in some strains associated with the gastrointestinal tract (Hyeong-Jun Lim 2004, Zhang et al 2008). In a previous study (unpublished), we investigated the cholesterol-lowering effect of lactic acid bacteria screened from Inner Mongolia native meat sausages in China. We defined the cholesterol-lowering effect of Lactobacillus plant arum X3-2B (L. p X3-2B)isolated from Inner Mongolia native meat sausages in vitro, and it was considered that the mechanism was incorporation of cholesterol into the L. p X3-2B. To verify our in vitro results and investigate the effectiveness of L. p X3-2B ingestion in decreasing the risk of atherosclerosis, we investigated the cholesterol-lowering effect of fecal micro biota, triglycerides (TG), total cholesterol (TC) and total bile acid, in rats to further characterize factors affecting and correlation of its ability to hydrolyze cholesterol
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: African Journal of Traditional, Complementary and Alternative Medicines
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
