Effects of Substituting Sedentary Behavior with Light-Intensity or Moderate-to-Vigorous Physical Activity on Obesity Indices in Adults: A Prospective Short-Term Follow-Up Study.

Bárbara De Barros Gonze,Evandro Fornias Sperandio,Victor Zuniga Dourado,Rodolfo Leite Arantes,Thatiane Lopes Valentim Di Paschoale Ostolin,Marcello Romiti

doi:10.3390/ijerph182413335

Bárbara De Barros Gonze, Evandro Fornias Sperandio + Show 4 more

Open Access

https://doi.org/10.3390/ijerph182413335

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Abstract

Background: Sedentary behavior (SB) is an independent risk factor for cardiovascular diseases. We hypothesized that there may be benefits of replacing SB with light-intensity (LIPA) and moderate-to-vigorous (MVPA) physical activity. Substituting SB with LIPA and MVPA might be associated with body composition changes. Methods: We assessed body weight, body mass index (BMI), fat body mass (FBM), and physical activity level, as well as one-year changes, in 780 adults (EPIMOV Study). Results: We analyzed into 10-min blocks SB, LIPA, MVPA, and total wear time. After 14 ± 3 months of follow-up, there were 242 completed procedures. We reallocated time spent in SB to LIPA or MVPA and assessed cross-sectional and prospective associations with the outcomes using isotemporal substitution models. In cross-sectional analysis, substituting 10-min blocks of SB with MVPA led to significant decreases of 1.23 kg in body weight, 0.30 kg/m² in BMI, and 0.38% in FBM. 10-min blocks substituting SB with LIPA produced significantly lower body weight (1 kg) and BMI (0.1 kg/m²) values. In longitudinal analysis, reallocating SB to MVPA was only associated with FBM decline (−0.31%). Conclusions: Substituting SB with MVPA is associated with significant improvement in obesity indices in both cross-sectional and follow-up. Replacing SB with LIPA produced a less consistent impact.

Highlights

Obesity is a growing public health problem worldwide and is commonly associated with several comorbidities [1]
The research on sedentary behavior (SB), which is defined as “any waking behavior characterized by an energy expenditure ≤1.5 metabolic equivalent of task (METs) while in a sitting, reclining or lying posture” [4], has increased in the past few years, but still presents several gaps, especially when it is considered that even terminology consensus is recent [5,6,7]
We investigated the effects of replacing SB by light-intensity physical activity (LIPA) and moderate-to-vigorous physical activity (MVPA) by using isotemporal substitution modeling

Summary

Introduction

Obesity is a growing public health problem worldwide and is commonly associated with several comorbidities [1]. The increase in energy expenditure provided by physical activity (PA), as well as its health benefits and its inverse relationship with obesity and mortality, are already well described in the literature [3]. Substituting SB with LIPA and MVPA might be associated with body composition changes. Methods: We assessed body weight, body mass index (BMI), fat body mass (FBM), and physical activity level, as well as one-year changes, in 780 adults (EPIMOV Study). We reallocated time spent in SB to LIPA or MVPA and assessed cross-sectional and prospective associations with the outcomes using isotemporal substitution models. In cross-sectional analysis, substituting 10-min blocks of SB with MVPA led to significant decreases of 1.23 kg in body weight, 0.30 kg/m2 in BMI, and 0.38%

Methods

Results

Discussion

Conclusion