Abstract
We have previously reported that the noradrenaline concentration in the rat tail artery increases after 10 weeks of STZ diabetes [1]. The aim of this study was to investigate whether the concentration of NPY also changes in the same manner. NPY is synthesized in the cell body and transported to the periphery of the axon, whereas noradrenline is synthesized in the varicosities; and differences in the two may be explained by changes in axonal transport. It has been suggested that retrograde transport is impaired in diabetes, and it is possible that the anterograde transport of materials is similarly affected, even though different transport systems may operate in the orthograde direction.
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