Abstract
Soy protein isolate hydrolysates (SPIH) were prepared from soy protein isolate (SPI). Effects of SPIH on a satiety signal cholecystokinin (CCK) and feeding behavior in rats were investigated. SPIH induced more CCK release (164.66 ± 2.40pg/mL) by rat intestinal mucosal cells than SPI (143.33 ± 3.71pg/mL). Meal size (MS), intermeal interval (IMI), and satiety ratio (SR = MS/IMI) of rats received different daily doses of SPIH or dietary fiber were detected for 40days. A 100mg/kg dose of SPIH resulted in a greater SR than an identical dose of dietary fiber, while a 300mg/kg dose resulted in a less MS and IMI. A 500mg/kg dose of SPIH had similar effects to the same dose of dietary fiber on reducing MS, extending IMI, and increasing SR, but resulted in a significantly less body weight at the end of the experiment (318.15 ± 17.83g) than the dietary fiber group (340.28 ± 6.15g).
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