Abstract
We previously reported that the infusion and the methanol extract from the aerial parts of Hypericum reflexum L. fil., an endemic species of the Canary Islands, showed antidepressant activity in mice [1, 2]. Preliminary phytochemical analysis carried out with the methanol extract of this species reveals the presence of flavonoids, tannins, saponins and anthraquinones. The presence of hypericin could not be detected in the crude methanol extract. On the basis of these results, the present study was undertaken to evaluate the antidepressant activity of the aqueous, butanol and chloroform fractions obtained from the methanol extract of this plant on the forced swimming test in mice. Also the effects of these fractions on locomotor activity, body temperature and sleep potentiation were evaluated. Student's t-test was used to verify the statistical significance.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
