Abstract
Ginger (Zingiber officinale) is a popular spice which is used for the treatment of different gastrointestinal and inflammatory discomfort. In the present study, the total phenolic content (TPC) and antioxidant activity of ginger extract using four solvents (ethanol, methanol, acetone, and ethyl acetate) were determined. Among the four solvents, methanol extract showed the maximum phenolic content (1183.813 mg GAE/100 g at Ayikel and 1022.409 mg GAE/100 g at Mandura) and the least phenolic content was found in acetone extract (748.865 mg GAE/100 g at Ayikel and 690.152 mg GAE/100 g at Mandura). In addition, the highest DPPH radical scavenging activity (84.868% at Ayikel and 82.883% at Mandura) was observed in methanol. However, acetone showed the least DPPH radical scavenging activity (73.864% at Ayikel and 70.597% at Mandura). Antioxidant activities of ginger extracts were also expressed as IC50 values, and acetone extract has maximum IC50 value (0.654 and 0.812 mg/mL) followed by ethyl acetate and ethanol, while being the lowest for methanol (0.481 and 0.525 mg/mL). The result of this study showed that extraction solvents significantly affected the total phenolic content and antioxidant activities of ginger. Thus, ginger can be regarded as promising candidates for natural sources of antioxidants with a high value of phenolic contents.
Highlights
Natural bioactive compounds especially plant sources have been investigated for their characteristics and health effects [1]
Total Phenolic Content. e total phenolic contents were determined by plotting the standard calibration curve of different concentrations of gallic acid using a spectrophotometer at 760 nm. e values of TPC were calculated as gallic acid equivalents (GAE) per 100 gram of dry weight
E amount of total phenolic content in ginger samples collected from Ayikel and Mandura was influenced significantly by extracting solvent (p < 0.05), and the contents were varied within the range of 690.152 to 1183.813 mg of GAE/100 g of dry weight for acetone and methanol, respectively
Summary
Natural bioactive compounds especially plant sources have been investigated for their characteristics and health effects [1]. Many spices such as cardamom, long pepper, black cumin, ginger, bishops weed, and coriander are highly cultivated in Ethiopia over many years. Ginger has been employed as an alternative medicine around the world for antiarthritic activity [4], protects against gastrointestinal ulcers, improves blood circulation, lowers blood glucose in the treatment of diabetes [5], and diarrhea [6]. Several studies revealed that ginger has showed antioxidant activity against lipid oxidation and oxidative stress [13, 14]
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