Abstract
We have studied the phase behavior of dipalmitoylphosphatidylcholine (DPPC) containing sodium β-sitosteryl sulfate (PSO4). PSO4 was found to lower the phase transition temperature of DPPC to a higher degree than cholesterol or β-sitosterol. It also gave rise to the formation of a modulated (ripple) phase (Pβ) at low to moderate concentrations. At concentrations greater than 25 mol%, it completely changed the membrane into a fluid phase. This shows that PSO4 is capable of disordering the hydrocarbon chains of PC efficiently. The characteristics of PSO4 for fluidizing the membrane can be useful for the pharmaceutical and cosmetics industries.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
