EFFECTS OF SEVOFLURANE, PROPOFOL, AND COMBINATION OF SEVOFLURANE AND PROPOFOL FOR CLASSIC LARYNGEAL MASK AIRWAY INSERTION IN ADULTS- A CLINICAL COMPARATIVE STUDY

Abstract

Background and Aims:Although LMA insertion is less invasive than endotracheal intubation,it also requires adequate mouth opening and blunting of minimal airway reflexes. Propofol is considered an appropriate IV agent for LMA insertion owing to its prompt induction and suppression of airway reflexes but induction doses required are often associated with hypotension,pain and apnea.Sevoflurane on the other hand,has minimal respiratory irritability,better hemodynamic stability and less apnea, but is associated with delayed jaw relaxation. Our hypothesis is that the combination of sevoflurane and propofol may be of better outcome whereby the insertion conditions of the LMA may be optimized adequately,at the same time the potential side-effects of individual drugs are effectively curtailed. Methods: 90 patients aged 20-60yrs of ASA I and II, 30 in each group were induced with Propofol (2mg/kg) in Group P, 8% Sevoflurane in N O: O (67%:33%) TVB technique in Group S and Group SP with additional propofol (1mg/kg) in 2 2 Group SP after loss of eyelash reflex. Induction characteristics, hemodynamic parameters and complications were observed. Results: 87% of the patients of Group SP had successful LMA insertion at first attempt, compared to 53% and 40% in Group P and Group S respectively, which was statistically significant. Less apnea was seen in Group SP(20%) as compared to Group P(60%),which was statistically significant. Conclusion: Our study showed that the combination group stood out to be the best with highest successful LMA insertion at first attempt and less incidence of apnea.