Abstract

Summary1. Rats fed a diet containing 20% corn oil have significantly lower concentrations of serum cholesterol than those fed equal amounts of coconut oil but both high-fat diets lead to elevation of serum cholesterol above that seen on control diets. 2. There is a very marked increase in esterified cholesterol of livers of rats fed corn oil whereas coconut oil-fed rats show no significant changes in liver cholesterol compared to controls. 3. Rate of incorporation of 1-C14-acetate or of T2O is higher in corn oil-fed rats than in others. 4. Some implications with respect to the mechanism by which unsaturated fats alter cholesterol metabolism are discussed.

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