Abstract

This study was to determine the mechanism underlying the hypoglycaemic activity of the aqueous extract perfusion of rosemary in normal and streptozotocin-induced diabetic rats. The sugar level and lipid profile were investigated in plasma of normal and streptozotocin-induced diabetic rats treated with rosemary for four weeks. Diabetic rats exhibited an increase in the levels of sugar, cholesterol, triglycerides and low density lipoprotein (LDL), and a decrease in the level of high density lipoprotein (HDL). The administration of rosemary showed a decrease of 20% in sugar level, 22% cholesterol, 24% triglycerides, 27% (LDL), and increase 18% in (HDL). The findings of this study indicate that the administration of rosemary shows better lipid profile as well as decrease in the sugar level in both normal and diabetic rats.

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