Abstract
The systematic review aimed to analyze the effects of resistance training in knee osteoarthritis (OA) rehabilitation from a biomechanical perspective. A meta-analysis was performed to determine the potential benefits of resistance training on patients with knee OA. Relevant studies based on the inclusion and exclusion criteria were selected from CENTRAL, PubMed, Scopus, and Web of Science databases inception to August 2020. Outcome measures included gait velocity and knee adduction moment (KAM). The mean differences of the data with a 95% confidence interval were analyzed using STATA 15.1 software The search identified eight studies that satisfied all the inclusion criteria, in which 164 patients were involved in gait velocity studies and another 122 patients were part of KAM studies. Analysis of the pooled data showed that resistance training significantly improved the gait velocity in patients with knee OA (p < 0.01, z = 2.73), ES (95% CI) = 0.03 (0.01, 0.06) m/s. However, resistance training had no significant effect on improving KAM in patients with knee OA (p = 0.98, z = 0.03), ES (95% CI) = 0.00 (− 0.16, 0.16) percentage of body weight × height (%BW × Ht). Therefore, resistance training may enhance gait velocity but not KAM in knee OA patients. The protocol was registered at PROSPERO (registration number: CRD42020204897).
Highlights
Materials and methodsInformation extracted from each study included the first author, year of publication, study design, age group and gender of patients, adverse events, type of training program, intervention duration, as well as the results of main indicators captured at baseline and final point (Table 1)
The systematic review aimed to analyze the effects of resistance training in knee osteoarthritis (OA) rehabilitation from a biomechanical perspective
Gait velocity was significantly increased (p = 0.014) by 3% in the training group compared to a 3% decrease in the control group
Summary
Information extracted from each study included the first author, year of publication, study design, age group and gender of patients, adverse events, type of training program, intervention duration, as well as the results of main indicators captured at baseline and final point (Table 1). All relevant studies that met these two criteria must report at least one of the variables being investigated, either gait velocity and/or KAM. All randomized controlled trials (RCT) and non-RCT studies published in English were included, whereas abstracts, conference proceedings, or presentations were excluded. Based on the total scores, the quality of each study was classified as “poor”, “fair” or “good”. The methodology in this systematic review was based on the guidelines in the Meta-Analysis Report Quality statement[24]
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