Abstract
Relationship between environmental pollution and lung cancer has not been fully clarified. There are particles with aerodynamic mass below 2.5 m, capable of directly injuring the lung due to their small size. The majority arise from the burning of fossil combustibles, and are called residual oil fly ash (ROFA).
Highlights
Lung cancer is at present of high incidence in the world (12.9% of all new cases) arising as the most frequent cause of cancer death [1], with a prospective of becoming the fifth general cause of death in 2020 [2].The relationship between lung cancer and environmental pollution is clear [3,4,5]
The majority arise from the burning of fossil combustibles, and are called “residual oil fly ash” (ROFA)
The histological study of the lungs revealed the presence of neoplastic nodules and hyperplasia, as well as the deposition of anthracotic pigment in the lungs of mice exposed to ROFA (Figure 1)
Summary
The relationship between lung cancer and environmental pollution is clear [3,4,5]. Environmental air contains an immense variety of known carcinogens present in the form of chemical compounds of various types. Their formation follows mainly the combustion of fossil fuels used to generate energy in industry and means of transportation. Among these components, smaller particle materials with aerodynamic masses below 2.5 μm (MW2.5) which, due to their small size can directly reach the pulmonary alveoli present a higher capacity of injury
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