Abstract
Review question / Objective: P:Adult patients (age ≥ 18 years) diagnosed with stroke based on relevant clinical examination; I:Intervention group with rTMS alone or in combination with other treatments with rTMS; C:Control group received sham treatment or no rTMS; O: Upper extremity function:the Fugl-Meyer Assessment Upper Extremity (FMA-UE); Hand function:box and block test(BBT), nine-hole peg test(NHPT), and Purdue pegboard test(PPT); S:Randomized controlled trials (rather than crossover designs). Condition being studied: In Europe, more than 1 million new cases of stroke are reported each year. The absolute number of stroke patients is expected to increase in the near future due to the progressive aging of the population. Approximately 50-80% of stroke survivors present with upper extremity dysfunction. Recovery of upper extremity function is associated with improvements in activities of daily living and mental health. However, few stroke survivors show full recovery of upper extremity function 6 months after stroke. In addition, rehabilitation has a limited impact on the recovery of hand motor function.
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