Effects of raw red beetroot consumption on metabolic markers and cognitive function in type 2 diabetes patients.

Abstract

This study aimed to investigate the effects of raw red beetroot consumption on metabolic markers and cognitive function in type 2 diabetes patients. In a quasi-experimental study, 44 type 2 diabetes patients (57 ± 4.5years) consumed raw red beetroot (100g, daily), for 8weeks. Metabolic markers including body weight, glucose and lipid profile parameters, inflammatory and oxidative stress markers, paraoxonase-1 activity, hepatic enzymes, blood pressure and cognitive function were measured at the beginning and end of 8weeks. Raw red beetroot consumption resulted in a significant decrease in fasting blood sugar (FBS) levels (-13.53mg/dL), glycosylated hemoglobin (HbA1c)(-0.34%), apolipoproteinB100 (ApoB100) (-8.25mg/dl), aspartate aminotransferase (AST) (-1.75U/L), alanine aminotransferase (ALT) (-3.7U/L), homocysteine (-7.88μmol/l), systolic (-0.73mmHg) and diastolic blood pressure (-0.34mmHg), anda significant increase in total antioxidant capacity (TAC) (105μmol/L) and cognitive function tests (all P values <0.05). Other variables did not change significantly after the intervention. Raw red beetroot consumption for 8weeks in T2DM patients has beneficial impacts on cognitive function, glucose metabolism and other metabolic markers.