Effects of Radiation Therapy in Adult Soft-Tissue Sarcomas (STS) of the Extremities (Ext): A 20-Year Retrospective Review

Abstract

STS are a rare neoplasm that should be evaluated and treated in a multidisciplinary sarcoma center. The goals of treatment (Tx) are improve survival, prevent local recurrence (LR), preserve function, and minimize morbidity. We report a retrospective analysis of a 20-year experience of a multidisciplinary community-based sarcoma center in the Tx of patients (pts) with Ext STS. Our purpose was to determine the effect of RT on the overall survival (OS), LR, and to report on major long term complications (MLTC) including pathologic fracture (pFx), amputation (Amp), and radiation induced sarcoma (RIS) for these pts.