Abstract
Purpose: The articular cartilage exhibits a limited ability for self-healing in adult individuals. Gene therapy using rAAV vectors is a promising tool to treat cartilage lesions but the presence of neutralizing antibodies against AAV capsid elements in a majority of patients remains a limitation to the use of these vectors in the clinics. Carbon dots (CDs), a new class of nanocarriers capable of transferring plasmid DNA in several cell lines [1], may provide effective platforms to deliver rAAV as a means to overcome such a limitation.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
