Abstract
In order to detect the effects of proximal gastric vagotomy on the gastrointestinal transit time during the early and late postoperative periods, a mixed solid-liquid test meal containing 0.5 mCi 99mTC colloid, 10 g lactulose and 750 mg indigocarmine was given to 10 patients with chronic duodenal ulcer disease 3 days prior to and 7 and 90 days after proximal selective vagotomy. In addition, the mouth-to-cecum transit time was measured on the 1 st and 3rd postoperative day. The rate of gastric emptying was determined by an anterior gamma camera technique, mouth-to-cecum transit time by the hydrogen breath test and whole gut transit time by the first appearance of indigocarmine in the stool. The preoperative data were compared to those of a control group (n = 20), not leading to any significant differences. In the early postoperative period, gastric emptying and whole gut transit time were delayed 7 days after operation as compared to the preoperative data. Three months after the operation no significant changes of gastrointestinal transit could be detected in comparison with the preoperative period.
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