Abstract
Monkey arachnoid villi fixed without controlling the pressures in the subarachnoid space or the venous sinus were irregularly distended. The endothelial cells showed a large number of clear vesicular spaces. In addition there were many greatly enlarged intercellular spaces. Villi fixed with a pressure difference of 10 cm of water between the subarachnoid space and the superior sagittal sinus were more regularly distended. The endothelial cells were stretched and separated by shortened and intermittently widened intercellular spaces. The degree of widening varied greatly. Most of the widenings were minor but a few were relatively large. Many intercellular spaces were permeable to horseradish peroxidase.
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