Abstract

Many prehospital factors that are known to influence survival rates after out-of-hospital cardiac arrest (OHCA) have been rarely studied as to how their influence varies depending on the age. In this study, we tried to find out what prehospital factors affect the survival rate after OHCA by age groups and how large the effect size of those factors is in each age group. We used the South Korean OHCA registry, which includes information on various prehospital factors relating OHCA and final survival status. The association between prehospital factors and survival was explored through logistic regression analyses for each age group. The effects of prehospital factors vary depending on the patient’s age. Being witnessed was relatively more influential in younger patients and the presence of first responders became more important as patients became older. While bystander cardiopulmonary resuscitation (CPR) did not appear to significantly affect survival in younger people, use of an automated external defibrillator (AED) showed the largest effect size on the survival in all age groups. Since the pathophysiology and etiologies of OHCA vary according to age, more detailed information on life support by age is needed for the development and application of more specialized protocols for each age.

Highlights

  • Out-of-hospital cardiac arrest (OHCA) is a global health problem that affects 55 people per100,000 people worldwide, but the survival rate varies significantly from community to community [1,2].Many studies have attempted to identify factors affecting the survival rate after OHCA

  • Survival proportions were higher in cases where OHCA was witnessed, was seen by a first responder, or occurred in public places, and cardiopulmonary resuscitation (CPR) or automated external defibrillator (AED) was performed

  • Our research shows that the relative importance of basic life support (BLS) to advanced life support (ALS) for survival is different because the cause of OHCA is age-dependent, and the survival rate in OHCA due to coronary artery disease (CAD) can only rise if all elements of BLS are performed together

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Summary

Introduction

Out-of-hospital cardiac arrest (OHCA) is a global health problem that affects 55 people per. Many studies have attempted to identify factors affecting the survival rate after OHCA. A series of actions are needed, including the immediate recognition of the cardiac arrest and the activation of an emergency response system, early cardiopulmonary resuscitation (CPR), rapid defibrillation, effective advanced life support, and integrated treatment after cardiac arrest [7,8]. Past medical literature had focused more on hospitals and advanced life-sustaining treatments than problems related to community care and basic life-sustaining. In recent years, awareness of the importance of basic life support (BLS), the role of the community, and the key functions of emergency medical dispatch in coordinating bystander CPR and early defibrillation has increased [9,10]

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