Abstract

A combined clinical and histologic study was carried out to determine the effects of prednisolone on the postoperative thermal sensitivity and pulpal reactions of teeth restored with Class V silicate cement restorations. Blinded and coded determinations of sensitivity to heat and cold, vitality tests, and histologic examinations of serial sections were performed. Based on a comparison between pairs of experimental and control teeth within the same patients, prednisolone was more effective in reducing thermal sensitivity than a placebo, and also resulted in a milder inflammatory reaction in the pulp. The use of prednisolone to reduce postoperative sensitivity should be an adjunct and not a substitute for other means of pulpal protection usually employed in restorative dentistry. The histologic portion of this study was carried out with the technical assistance of Miss Edna M. Preader.

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