Abstract

Seven female Wistar rats were fed a liquid diet containing Sustagen and ethanol through Days 1–17 of lactation. Six control females were pair-fed an identical liquid diet except for isocaloric substitution of sucrose for ethanol. Continuous monitoring of maternal nesting behavior, employing automated nesting chambers, indicated that the mothers fed ethanol spent more time on the nest nursing their young than the pair-fed controls during the middle of the observation period. This increase in nesting time may be due to a decrease in activity in the ethanol-fed mothers or due to greater heat loss in their pups, allowing them to remain longer on the nest. This increased nesting time occurs when the pups’ motor effectiveness and exploratory drive are developing, and may account for the long-term behavioral changes seen in the pups.

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