Abstract
ABSTRACT In three strains of mice and an outcross of each to ZRDCT-An, the fetuses occupying the implantation site nearest the common uterus are less likely to survive than the ones nearest the ovary. When dams are treated with trypan blue, mortality in excess of the spontaneous frequency seems greater in the ovarian than in the cervical position. Both the heterogeneity of distribution of spontaneous mortality and the suggestion of treatment-position interaction show the importance of intra-uterine selection upon survival of a developing organism. None of the data are inconsistent with the hypothesis that one mechanism of selection is through variations in blood supply in different regions of the uterus.
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