Abstract

In this study, the effects of polymer flexibility and entanglement on elastic instability were investigated by observing sodium hyaluronate (Hyaluronic Acid Sodium salt, Na-HA) solution in planar abrupt contraction-expansion microchannels. The rigidity of Na-HA in a solution is affected by ion concentration in the solution. Therefore, we prepared Na-HA water solution and Na-HA PBS solution with concentrations from 0.15 wt% to 0.45 wt%. The rheological properties were measured and analyzed to detect the Na-HA overlap and entanglement concentrations. The flow regimes of the Na-HA solutions in several planar abrupt contraction-expansion channels were characterized in terms of rheological properties, polymer flexibility and polymer entanglement.

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