Abstract
A single intraperitoneal injection of any one of several polycyclic aromatic hydrocarbons given to young Amazon mollies induces massive enlargement of the spleen. This enlargement is the result of splenic tissue being partially or wholly replaced by proliferating thyroid tissue. The pharyngeal thyroid gland is stimulated but to a lesser degree. No exuberant thyroid tissue is found at any other extrapharyngeal site. We discuss the possible causes of this finding.
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