Effects of PM2.5 on Cardio-Pulmonary Function Injury in Open Manganese Mine Workers.

Yuanni Huang,Mian Bao,Kusheng Wu,Jiefeng Xiao,Zhaolong Qiu

doi:10.3390/ijerph16112017

Abstract

Exposure to fine particulate matter 2.5 (PM2.5) is associated with adverse health effects, varying by its components. The health-related effects of PM2.5 exposure from ore mining may be different from those of environment pollution. The aim of this study was to investigate the effects of different concentrations of PM2.5 exposure on the cardio-pulmonary function of manganese mining workers. A total of 280 dust-exposed workers who were involved in different types of work in an open-pit manganese mine were randomly selected. According to the different concentrations of PM2.5 in the working environment, the workers were divided into an exposed group and a control group. The electrocardiogram, blood pressure, and multiple lung function parameters of the two groups were measured and analyzed. The PM2.5 exposed group had significantly lower values in the pulmonary function indexes of forced expiratory volume in one second (FEV1.0), maximum mid expiratory flow (MMEF), peak expiratory flow rate (PEFR), percentage of peak expiratory flow out of the overall expiratory flow volume (PEFR%), forced expiratory flow at 25% and 75% of forced vital capacity (FEF 25, FEF75), forced expiratory flow when 25%, 50%, and 75% of forced vital capacity has been exhaled (FEF25%,FEF50%, FEF75%), and FEV1.0/FVC% (the percentage of the predicted value of forced vital capacity) than the control group (all p < 0.05). Both groups had mild or moderate lung injury, most of which was restrictive ventilatory disorder, and there was significant difference in the prevalence rate of restrictive respiratory dysfunction between the two groups (41.4% vs. 23.6%, p = 0.016). Electrocardiogram (ECG) abnormalities, especially sinus bradycardia, were shown in both groups, but there was no statistical difference of the prevalence rate between the two groups (p > 0.05). Also, no significant difference of the prevalence rate of hypertension was observed between the PM2.5 exposure and control groups (p > 0.05). PM2.5 exposure was associated with pulmonary function damage of the workers in the open-pit manganese mine, and the major injury was restrictive ventilatory disorder. The early effect of PM2.5 exposure on the cardiovascular system was uncertain at current exposure levels and exposure time.

Highlights

IntroductionMined ore needs to be broken, screened, and beneficiated to obtain the necessary minerals
Mined ore needs to be broken, screened, and beneficiated to obtain the necessary minerals.The production process is often accompanied by direct or indirect emissions of particulars of different diameters
The results show that the main respiratory dysfunction was restrictive (Figure 1A), and the prevalence rate was higher in the exposed group than in the control group (41.4% vs. 23.6%)

Summary

Introduction

Mined ore needs to be broken, screened, and beneficiated to obtain the necessary minerals. The production process is often accompanied by direct or indirect emissions of particulars of different diameters. All kinds of fine particulate matter pollution occur in the process of mining, crushing, ball milling, and so on, through which it is easy to form a variety of aerosol particle sizes. The formation of fine particulate matter pollution concentrates heavy metals, organic pollutants, etc., and can be directly entered into the alveoli and the blood circulatory system. Res. Public Health 2019, 16, 2017; doi:10.3390/ijerph16112017 www.mdpi.com/journal/ijerph

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