Abstract
Female albino rabbits were subjected to bilateral sciatic and femoral neurectomy after a training period to accept sling restraint. Three animals were subjected to continuous and four to intermittent passive movement of the left hind limb for 21 days. The course of neurogenic atrophy and the development of limb edema and joint contracture were evaluated by electromyography, morphometric evaluation, and muscle histochemistry. Neurogenic atrophy was altered by the passive movement. The data suggest that the variability of lesser fiber diameter was reduced in type II fibers of the tibialis anterior muscle and type I fibers were unaffected in the soleus muscle. Structural alterations and endomysial fibrosis were greater in the tibialis anterior on the left; the soleus was relatively uninvolved. Fibrillations appeared 3 or more days earlier on the left. Limb edema and joint contractures were effectively prevented by passive movement.
Published Version
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